Thionyl Chloride → 2-(4-ethoxyphenyl)acetyl Chloride

HRID 1385894

반응식

HRID 1385894 반응식
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([OH:13])=O)=[CH:6][CH:5]=1)[CH3:2].S(Cl)([Cl:16])=O>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([Cl:16])=[O:13])=[CH:6][CH:5]=1)[CH3:2]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 78631Benzeneacetic acid, 4-ethoxy-

생성물 1

HCID 116297822-(4-ethoxyphenyl)acetyl Chloride

실험 절차

50 g (0.28 mol) of 4-ethoxyphenylacetic acid were treated with 50 ml of thionyl chloride and the mixture was stirred for 24 hours at room temperature. Excess thionyl chloride was removed in vacuo and the residue was distilled under a high vacuum. This gave 39 g (71% of theory) of an oil (boiling point 110° C./53.3 Pa).

후처리

  1. customExcess thionyl chloride was removed in vacuo
  2. distillationthe residue was distilled under a high vacuum

출처 및 근거

ORD 기록
ord-ab873478ff5c4224a1fffcfd1c5328c0
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06265398B1

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