(4-Methoxyphenyl)boronic acid → 2-(4-Methoxyphenyl)-3-(4-methoxyphenoxy)benzo[b]thiophene

HRID 1386986

반응식

HRID 1386986 반응식
I[C:2]1[S:6][C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[C:3]=1[O:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1.[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25](B(O)O)=[CH:24][CH:23]=1>CCOC(C)=O>[CH3:19][O:18][C:15]1[CH:16]=[CH:17][C:12]([O:11][C:3]2[C:4]3[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=3[S:6][C:2]=2[C:25]2[CH:26]=[CH:27][C:22]([O:21][CH3:20])=[CH:23][CH:24]=2)=[CH:13][CH:14]=1

참가 물질

4

반응물 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 106912792-Iodo-3-(4-methoxyphenoxy)benzo[b]thiophene

생성물 1

HCID 117930042-(4-Methoxyphenyl)-3-(4-methoxyphenoxy)benzo[b]thiophene수율 70%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

By essentially following the procedure detailed in Example 1, Part B, the title compound was prepared from 2-iodo-3-(4-methoxyphenoxy)benzo[b]thiophene (Part B) and (4-methoxyphenyl)boronic acid (Part C) in 70% yield following chromatography (SiO2; 5% EtOAc in hexanes).

출처 및 근거

ORD 기록
ord-c0ce58324bd54ddb9494a30ba4e3b937
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06265575B1

연결된 노트

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