Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl chloroformate → 5-Ethoxycarbonylamino-4-chloro-2-[2-(2,4-di-tert-amylphenoxy)butanamido]phenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl chloroformate | HCID 10928 | — |
| 반응물 | 2-{2-(2,4-Di-t-amylphenoxy)butanamido}-4-chloro-5-aminophenol | HCID 20036192 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 5-Ethoxycarbonylamino-4-chloro-2-[2-(2,4-di-tert-amylphenoxy)butanamido]phenol | HCID 20471931 | — |
반응 단계
42 g of the 5-amino-4-chloro-2-[2-(2,4-di-tert-amylphenoxy)butanamido]phenol obtained in Step (i) above was dispersed in acetonitrile to which 10.4 g of ethyl chloroformate was added dropwise under refluxing. After refluxing for 3 hours, the reaction mixture was cooled to deposite crystals. The crystals were collected by filtration and dried to obtain 41.8 g of the above described compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04430423 |
| 출처 데이터셋 | uspto-grants-1984_02 |
| ORD ID | ord-d18690cbd9534404bf141d0c25842912 |
| 출처 메모 | uspto-grants-1984_02 |