4-Chloroaniline → N-(4-chlorophenyl)isoleucine

HRID 1389357노트

반응식

HRID 1389357 반응식
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[Na].Br[CH:11]([CH:15]([CH3:18])[CH2:16][CH3:17])[C:12]([OH:14])=[O:13]>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C@H:11]([C:12]([OH:14])=[O:13])[C@H:15]([CH2:16][CH3:17])[CH3:18])=[CH:4][CH:3]=1

참가 물질

4

반응물 3

HCID 78124-ChloroanilineHCID 2604812-Bromo-3-methylpentanoic acidHCID 5360545Sodium

생성물 1

HCID 54011701N-(4-chlorophenyl)isoleucine

실험 절차

N-(4-chlorophenyl)isoleucine is prepared by the reaction of 4-chloroaniline with the sodium salt of α-bromo-3-methylpentanoic acid neat at 100°.

출처 및 근거

ORD 기록
ord-a81646a5d97748778422040a5719638b
출처 데이터셋
uspto-grants-1981_01
특허 번호
US04243819

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