Acetone → HCID 88766983, 화합물

HRID 1389961

반응식

HRID 1389961 반응식
[C:1]([CH2:3][CH2:4][PH:5](=[O:10])[CH2:6][CH2:7][C:8]#[N:9])#[N:2].[CH3:11][C:12]([CH3:14])=[O:13].CN(C)C(=NC)N(C)C>C(N(CC)CC)C>[CH3:11][C:12]([P:5](=[O:10])([CH2:6][CH2:7][C:8]#[N:9])[CH2:4][CH2:3][C:1]#[N:2])([OH:13])[CH3:14]

참가 물질

5

반응물 3

HCID 180AcetoneHCID 139457N,N,N',N',N''-PentamethylguanidineHCID 178511210HCID 178511210, 화합물

생성물 1

HCID 88766983HCID 88766983, 화합물수율 88%

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

To a mixture of 0.1 mol of bis(2-cyanoethyl)phosphine oxide and 0.1 mol of acetone was added 1.0 gram of either triethyl amine or pentamethyl guanidine. The mixture was heated for 2 hours at steam bath temperatures. The resulting solid was filtered and recrystallized from acetone to give an 88% yield of product, m.p. 124°-125° C.

후처리

  1. temperatureThe mixture was heated for 2 hours at steam bath temperatures
  2. filtrationThe resulting solid was filtered
  3. customrecrystallized from acetone

출처 및 근거

ORD 기록
ord-842a394f7c5a4c3cb602647f6bf0e708
출처 데이터셋
uspto-grants-1981_01
특허 번호
US04247447

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