Potassium Carbonate → 3-(Benzyloxy)piperidine

HRID 1390496노트

반응식

HRID 1390496 반응식
C([N:4]1[CH2:9][CH2:8][CH2:7][CH:6]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:5]1)(=O)C.[OH-].[Na+].C(=O)([O-])[O-].[K+].[K+]>O>[CH2:11]([O:10][CH:6]1[CH2:7][CH2:8][CH2:9][NH:4][CH2:5]1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 205061191-Acetyl-3-benzyloxypiperidine

생성물 1

HCID 199606043-(Benzyloxy)piperidine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

1-Acetyl-3-benzyloxypiperidine (0.043 mole), sodium hydroxide (0.086 mole) and water (30 ml.) are combined and refluxed for 24 hours. The reaction mixture is saturated with potassium carbonate and extracted three times with ether. The ether is removed by evaporation and the yellow oil is distilled at 92°-94° C. (0.3 mm Hg.).

후처리

  1. temperaturerefluxed for 24 hours
  2. extractionextracted three times with ether
  3. customThe ether is removed by evaporation
  4. distillationthe yellow oil is distilled at 92°-94° C. (0.3 mm Hg.)

출처 및 근거

ORD 기록
ord-b342f3901ed145b683d69f49a2bf3e13
출처 데이터셋
uspto-grants-1979_02
특허 번호
US04138399

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