Oxalic Acid → 3-(2-Nitrophenoxy)propane-1,2-diol
반응식
[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[O:6][CH2:7][CH:8]1[CH2:10][O:9]1)([O-:3])=[O:2].C(O)(=O)C(O)=[O:17].O1CCOCC1>O>[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[O:6][CH2:7][CH:8]([OH:17])[CH2:10][OH:9])([O-:3])=[O:2]참가 물질
5
실험 절차
To a stirred solution of 38 parts of 2-(2-nitrophenoxymethyl)-oxirane in 10 parts of ethanedioic acid and 300 parts of 1,4-dioxane are added 100 parts of water. The whole is stirred and refluxed for 2 days. The reaction mixture is evaporated and the residue is crystallized from a mixture of 2,2'-oxybispropane and petroleumether. The product is filtered off and recrystallized from 2,2'-oxybispropane, yielding 29.5 parts (13%) of 3-(2-nitrophenoxy)-1,2-propanediol; mp. 96° C.
후처리
- temperaturerefluxed for 2 days
- customThe reaction mixture is evaporated
- customthe residue is crystallized from a mixture of 2,2'-oxybispropane and petroleumether
- filtrationThe product is filtered off
- customrecrystallized from 2,2'-oxybispropane
출처 및 근거
- ORD 기록
- ord-5fc6e79ebd80409c98bafa500a6a8e2e
- 출처 데이터셋
- uspto-grants-1979_02
- 특허 번호
- US04139540
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