4-Nitrobenzyl chloride → 1-(4-Nitrobenzyl)-4-phenylpiperazine

HRID 1391008노트

반응식

HRID 1391008 반응식
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Cl)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.Cl.[C:14]1([N:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(N(CC)CC)C>[C:14]1([N:20]2[CH2:25][CH2:24][N:23]([CH2:8][C:7]3[CH:10]=[CH:11][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=3)[CH2:22][CH2:21]2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

4

반응물 2

HCID 74824-Nitrobenzyl chlorideHCID 77619Phenylpiperazine dihydrochloride

생성물 1

HCID 2594881-(4-Nitrobenzyl)-4-phenylpiperazine

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

In the manner given in Example 1A, p-nitrobenzyl chloride is reacted with phenylpiperazine dihydrochloride in the presence of triethylamine to give 1-phenyl-4-(p-nitrobenzyl)piperazine

출처 및 근거

ORD 기록
ord-a2efd700b2ad477d9fa8779e59668f4b
출처 데이터셋
uspto-grants-1979_02
특허 번호
US04140775

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