Pyrrolidine → 1-(1,1-Dimethyl-2-pyrrolidin-1-yl-ethyl)4-nitro-1H-imidazole

HRID 1392448노트

반응식

HRID 1392448 반응식
[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH:3]=O.[NH:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH2:3][N:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1

참가 물질

3

반응물 2

HCID 31268PyrrolidineHCID 866008092-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde

생성물 1

HCID 671651351-(1,1-Dimethyl-2-pyrrolidin-1-yl-ethyl)4-nitro-1H-imidazole

실험 절차

2-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde was reacted with pyrrolidine to provide the title compound: H1 NMR (400 MHz, CDCl3) 1.56 (s, 6H), 1.61 (m, 4H), 2.35 (m, 4H), 2.70 (m, 4H), 7.60 (s,1H), 7.92 (s, 1H); MS m/z 239.2 (M+1).

출처 및 근거

ORD 기록
ord-8694a7f5ef8b4668a126a37d3e4b3c16
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07342118B2

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