Sulfuric Acid → HCID 58018321, 화합물

HRID 1393070

반응식

HRID 1393070 반응식
[CH:1]([OH:4])([CH3:3])[CH3:2].S(=O)(=O)(O)O.[N+:10]([C:13]1[CH:34]=[CH:33][C:16]([CH2:17][C@@H:18]([C:30](O)=[O:31])[NH:19][C:20](=[O:29])[C:21]2[C:26]([Cl:27])=[CH:25][CH:24]=[CH:23][C:22]=2[Cl:28])=[CH:15][CH:14]=1)([O-:12])=[O:11]>O1CCCC1>[CH:1]([O:4][C:30](=[O:31])[C@H:18]([CH2:17][C:16]1[CH:15]=[CH:14][C:13]([N+:10]([O-:12])=[O:11])=[CH:34][CH:33]=1)[NH:19][C:20](=[O:29])[C:21]1[C:26]([Cl:27])=[CH:25][CH:24]=[CH:23][C:22]=1[Cl:28])([CH3:3])[CH3:2]

참가 물질

5

반응물 3

HCID 1118Sulfuric AcidHCID 3776IsopropanolHCID 58018322N-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanine

생성물 1

HCID 58018321HCID 58018321, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

반응 조건

온도
50 °C

실험 절차

Isopropanol (130 mL), tetrahydrofuran (50 mL) and sulfuric acid (0.44 mL) were added to 4-nitro-N-(2,6-dichlorobenzoyl)-L-phenylalanine (2.95 g, 7.70 mmol) and stirred at 50° C. for 5 days. After removing the solvent under reduced pressure, the obtained solid material was washed with water and dried to obtain 3.28 g of a white solid material.

후처리

  1. customAfter removing the solvent under reduced pressure
  2. washthe obtained solid material was washed with water
  3. customdried

출처 및 근거

ORD 기록
ord-7f0384011cc04bccb8a0f3eda6d020dd
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07345049B2

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