Methyl iodide → N-(4-Methoxyphenyl)-2,4-dinitroaniline

HRID 1393608노트

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HRID 1393608 반응식
[N+:1]([C:4]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)([O-:3])=[O:2].[C:21](=O)([O-])[O-].[K+].[K+].CI>CN(C)C=O>[N+:1]([C:4]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:21])=[CH:9][CH:8]=1)([O-:3])=[O:2]

참가 물질

5

반응물 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 38580814-(2,4-Dinitroanilino)phenol

생성물 1

HCID 260958N-(4-Methoxyphenyl)-2,4-dinitroaniline

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

1.43 g of 4-(2,4-dinitroanilino)phenol, 500 mg of potassium carbonate and 0.32 ml of methyl iodide were stirred in 5 ml of N,N-dimethylformamide for 2 days at 20° C. The mixture was poured onto water, extracted three times with ethyl acetate, the extracts were dried on sodium sulfate, concentrated by evaporation in a vacuum, and the residue was chromatographed on silica gel.

후처리

  1. additionThe mixture was poured onto water
  2. extractionextracted three times with ethyl acetate
  3. customthe extracts were dried on sodium sulfate
  4. concentrationconcentrated by evaporation in a vacuum
  5. customthe residue was chromatographed on silica gel

출처 및 근거

ORD 기록
ord-aed33f363a99435c923858b1921c5c1d
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07345075B2

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