Toluene → 2-Cyclopenten-1-one, 3-methyl-2-(3-methyl-2-butenyl)-

HRID 1393707

반응식

HRID 1393707 반응식
[CH3:1][C:2]1[CH2:6][CH2:5][C:4](=[O:7])[CH:3]=1.[CH2:8](Cl)[CH:9]=[C:10]([CH3:12])[CH3:11].C1(C)C=CC=CC=1.[OH-].[Na+]>CCCCCCCC[N+](CCCCCCCC)(CCCCCCCC)C.[Cl-].C(O)(=O)C.O>[CH3:1][C:2]1[CH2:6][CH2:5][C:4](=[O:7])[C:3]=1[CH2:8][CH:9]=[C:10]([CH3:12])[CH3:11]

참가 물질

8

반응물 4

HCID 1140TolueneHCID 104291-Chloro-3-methyl-2-buteneHCID 14798Sodium HydroxideHCID 176913-Methyl-2-cyclopenten-1-one

생성물 1

HCID 147584872-Cyclopenten-1-one, 3-methyl-2-(3-methyl-2-butenyl)-수율 49.9%

시약·촉매·용매 3

HCID 21218Trioctylmethylammonium chloride촉매HCID 176Acetic Acid용매HCID 962Water용매

반응 조건

온도
100 °C

실험 절차

A mixture of 3-methyl-2-cyclopentenone 24.5 g (0.25 mole) and prenyl chloride 54 g (0.51 mole) was fed into a reaction flask containing 30 ml of toluene, sodium hydroxide 21.3 g, water 21.3 g and Aliquat 336 1 g maintaining 100° C. The reaction mass was aged for 4 hours, cooled to 25° C. and neutralized with acetic acid. The organic layer was removed and distilled to give 20.5 g of 3-methyl-2-(3-methyl-2-butenyl)-2-cyclopenten-1-one.

후처리

  1. customwas fed into a reaction flask
  2. customThe organic layer was removed
  3. distillationdistilled

출처 및 근거

ORD 기록
ord-d8d0ea40733d4f2db6ee2f64a1dcd226
출처 데이터셋
uspto-grants-2008_03
특허 번호
US07345204B2

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