HCID 57942920, 화합물 → HCID 22461189, 화합물
반응식
[C:1]([O:5][C:6]([N:8]1[CH:12]=[CH:11][CH:10]=[C:9]1[C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([N+:19]([O-])=O)[CH:14]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pt]>[C:1]([O:5][C:6]([N:8]1[CH2:12][CH2:11][CH2:10][CH:9]1[C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([NH2:19])[CH:14]=1)=[O:7])([CH3:4])([CH3:2])[CH3:3]참가 물질
4
실험 절차
The product of Step 1 (7.5 g, 26.01 mmol), was dissolved in ethanol (125 ml), and treated with 5 wt % Platinum on charcoal (750 mg), and stirred under 1 atm of H2 for 4 days. The reaction was filtered and the filtrate evaporated in vacuo. The residue was purified by silica gel chromatography eluting with a mixture of ether/dichloromethane (5:95) to afford the title compound (4.2 g, 62%); MS (ES+) m/e 263 [M+H]+.
후처리
- filtrationThe reaction was filtered
- customthe filtrate evaporated in vacuo
- customThe residue was purified by silica gel chromatography
- washeluting with a mixture of ether/dichloromethane (5:95)
출처 및 근거
- ORD 기록
- ord-ab77cf7488b847bd8c7d538b15816fc2
- 출처 데이터셋
- uspto-grants-2008_03
- 특허 번호
- US07348339B2
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