Ammonia → Dimethyldipropylenetriamine

HRID 1395064

반응식

HRID 1395064 반응식
[CH3:1][N:2]([CH3:11])[CH2:3][CH2:4][CH2:5][NH:6][CH2:7][CH2:8][C:9]#[N:10].N>C(O)(C)C.[Ni]>[CH3:11][N:2]([CH3:1])[CH2:3][CH2:4][CH2:5][NH:6][CH2:7][CH2:8][CH2:9][NH2:10]

참가 물질

5

반응물 2

HCID 222AmmoniaHCID 1123223-{[3-(Dimethylamino)propyl]amino}propanenitrile

생성물 1

HCID 82728Dimethyldipropylenetriamine

시약·촉매·용매 2

HCID 935Nickel촉매HCID 3776Isopropanol용매

실험 절차

216 g of N,N-dimethyl-N'-(β-cyanoethyl)-1,3-diaminopropane are hydrogenated in 216 ml of isopropanol in the presence of 140 g of gaseous ammonia and 13 g of Raney nickel in an autoclave at 120° C. and under an initial pressure of 80 atmospheres until the pressure remains constant, which is already the case after 30 minutes. The catalyst is filtered off with suction, the filtrate is concentrated in a rotary evaporator and the residue is distilled through a packed column. Yield: 205.7 g (92.8%); boiling point 121° C./11 mm Hg.

후처리

  1. customafter 30 minutes
  2. filtrationThe catalyst is filtered off with suction
  3. concentrationthe filtrate is concentrated in a rotary evaporator
  4. distillationthe residue is distilled through a packed column

출처 및 근거

ORD 기록
ord-cb7ebbf5dae847e59f7395c398982eda
출처 데이터셋
uspto-grants-1980_05
특허 번호
US04201854

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