돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1397236생성일: 2026년 10월 26일

2-Bromo-1-(pyridin-4-yl)ethanone → 2-[4-(Pyridin-4-YL)-1,3-thiazol-2-YL]acetonitrile

https://huagongshe.com/reaction/1397236

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-1-(pyridin-4-yl)ethanoneHCID 407031—
반응물2-CyanoethanethioamideHCID 1416277—
생성물2-[4-(Pyridin-4-YL)-1,3-thiazol-2-YL]acetonitrileHCID 2471044746%

반응 단계

This compound was synthesized from 2-bromo-1-(pyridin-4-yl)ethanone and 2-cyanothioacetamide as described in example 1 step 1 (0.23 g, yield 46%): 1H NMR (300 MHz, MeOD) δ 8.59 (m, 2H), 8.24 (s, 1H), 7.98 (m, 2H), 4.44 (s, 2H). MS (ESI) m/z: Calculated for C10H7N3OS: 201.01. found: 202.2 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08901156B2
출처 데이터셋uspto-grants-2014_12
ORD IDord-a5d17cc95da94bd18a961cda1451e344
출처 메모uspto-grants-2014_12