Tetrahydrothiophene → 1-(2-Ethoxy-2-oxoethyl)thiolan-1-ium bromide

HRID 1397270노트

반응식

HRID 1397270 반응식
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9]>CC(C)=O>[Br-:6].[CH2:11]([O:10][C:8](=[O:9])[CH2:7][S+:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[CH3:12]

참가 물질

4

반응물 2

HCID 1127TetrahydrothiopheneHCID 7748Ethyl bromoacetate

생성물 1

HCID 162050281-(2-Ethoxy-2-oxoethyl)thiolan-1-ium bromide수율 82%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Tetrahydrothiophene (10 g, 113 mmol) and ethyl bromoacetate (13 mL, 113 mmol) were taken in acetone (50 mL) and stirred at room temperature for 3 days. The precipitate was filtered, washed with acetone and air dried to get 1-(2-ethoxy-2-oxoethyl)tetrahydro-1H-thiophenium bromide (23 g, yield 82%), which was carried through without further purification.

후처리

  1. filtrationThe precipitate was filtered
  2. washwashed with acetone and air
  3. customdried

출처 및 근거

ORD 기록
ord-1e50d8cdbb0c4c389fdce7d71165dd62
출처 데이터셋
uspto-grants-2014_12
특허 번호
US08901156B2

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