methyl 3-(2,3-dichlorobenzyl)-2-methyl-5-morpholino-3H-imidazo[4,5-b]pyridine-7-carboxylate → 3-(2,3-dichlorobenzyl)-2-methyl-5-morpholino-3H-imidazo[4,5-b]pyridine-7-carboxylic acid
반응식
[Cl:1][C:2]1[C:28]([Cl:29])=[CH:27][CH:26]=[CH:25][C:3]=1[CH2:4][N:5]1[C:9]2=[N:10][C:11]([N:18]3[CH2:23][CH2:22][O:21][CH2:20][CH2:19]3)=[CH:12][C:13]([C:14]([O:16]C)=[O:15])=[C:8]2[N:7]=[C:6]1[CH3:24]>[Li+].[OH-].C1COCC1>[Cl:1][C:2]1[C:28]([Cl:29])=[CH:27][CH:26]=[CH:25][C:3]=1[CH2:4][N:5]1[C:9]2=[N:10][C:11]([N:18]3[CH2:23][CH2:22][O:21][CH2:20][CH2:19]3)=[CH:12][C:13]([C:14]([OH:16])=[O:15])=[C:8]2[N:7]=[C:6]1[CH3:24]참가 물질
4
반응 조건
- 온도
- 60 °C