Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl chloroacetate → Glycine, N-(4-chlorophenyl)-, ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl chloroacetate | HCID 7751 | — |
| 반응물 | 4-Chloroaniline | HCID 7812 | — |
| 반응물 | Sodium Acetate Trihydrate | HCID 23665404 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Glycine, N-(4-chlorophenyl)-, ethyl ester | HCID 302644 | 55.9% |
반응 단계
Sodium acetate trihydrate (6 g) was added to a solution of commercial ethyl chloroacetate (6.2 g) and commercial 4-chloroaniline (6.4 g) in ethanol (5 ml). The mixture was heated to reflux for 5 h. After cooling in an ice bath the product precipitates. The solid was collected by suction filtration and washed with water. The still wet product was recrystallised from ethanol to give ethyl N-(4-chlorophenyl)glycinate (5.99 g) as greyish crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08912186B2 |
| 출처 데이터셋 | uspto-grants-2014_12 |
| ORD ID | ord-f4611cbfb3fb4deea75c22e6bec2aa55 |
| 출처 메모 | uspto-grants-2014_12 |