Formamide → 4-Chloro-phthalimide

반응식

[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=O)[O:8][C:6](=[O:7])[C:5]2=[CH:11][CH:12]=1.C([NH2:15])=O>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[O:8])[NH:15][C:6](=[O:7])[C:5]2=[CH:11][CH:12]=1

참가 물질

반응물 2

HCID 713Formamide

HCID 670444-Chlorophthalic anhydride

생성물 1

HCID 2312394-Chloro-phthalimide

반응 조건

온도: 150 °C

실험 절차

The suspension of 4-chlorophthalic anhydride (3 g) in formamide (15 ml) was heated with stirring to 150° C. for 1 h. The resulting yellowish solution was cooled to rt and the product was fractionally precipitated by addition of water to yield 4-chlorophthalimide (1.91 g) as colourless crystals.

후처리

temperaturewas heated
temperatureThe resulting yellowish solution was cooled to rt
customthe product was fractionally precipitated by addition of water

출처 및 근거

ORD 기록: ord-a4d8cdbd42d94e47b4b7adb10aff1b6f
출처 데이터셋: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08912186B2

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