Sodium Hydroxide → 4-Methoxy-7h-pyrrolo[2,3-d]pyrimidine
반응식
Cl[C:2]1[C:3]2[CH:10]=[CH:9][NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.Cl[C:12]1[N:13]=[CH:14][C:15]2[CH:20]=[CH:19][NH:18][C:16]=2[N:17]=1.[OH-:21].[Na+]>CO>[CH3:12][O:21][C:2]1[C:3]2[CH:10]=[CH:9][NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:2][O:21][C:12]1[N:13]=[CH:14][C:15]2[CH:20]=[CH:19][NH:18][C:16]=2[N:17]=1참가 물질
6
실험 절차
4-methoxy-7H-pyrrolo[2,3-d]pyrimidine (3) or 2-methoxy-7H-pyrrolo[2,3-d]pyrimidine (4) is prepared by reacting 4-chloro-7H-pyrrolo[2,3-d]pyrimidine (1) or 2-chloro-7H-pyrrolo[2,3-d]pyrimidine (2), respectively, with sodium hydroxide in methanol as described by Girgis, N. et. al., J. Heterocyclic. Chem. 1989, 26:317-325.
출처 및 근거
- ORD 기록
- ord-f12e49dc8ffb4e89b6f0d636d97b6043
- 출처 데이터셋
- uspto-grants-2014_12
- 특허 번호
- US08912204B2
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