Ammonia → 3-Fluoro-4-(4-methoxy-phenoxy)-benzylamine
반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)[CH:5]=O.[NH3:19]>[Ni]>[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)[CH2:5][NH2:19]참가 물질
4
반응 조건
- 온도
- 35 °C
실험 절차
73.9 mg (0.3 mmol) of 3-fluoro-4-(4-methoxy-phenoxy)-benzaldehyde are dissolved in 5 ml of methanolic ammonia, combined with Ra—Ni and shaken for about 9 hours at 35° C. and 3 bar H2 pressure.
출처 및 근거
- ORD 기록
- ord-d8b5367d71c94ce6a4b191e15f18e3dc
- 출처 데이터셋
- uspto-grants-2014_12
- 특허 번호
- US08916589B2
반응 노트
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