HCID 86658821, 화합물 → 1-[4-(4-Difluoromethoxy-phenoxy)-phenyl]-ethylamine
반응식
[F:1][CH:2]([F:21])[O:3][C:4]1[CH:20]=[CH:19][C:7]([O:8][C:9]2[CH:14]=[CH:13][C:12]([C:15](=[N:17]O)[CH3:16])=[CH:11][CH:10]=2)=[CH:6][CH:5]=1.[H][H]>N.[Ni]>[F:1][CH:2]([F:21])[O:3][C:4]1[CH:20]=[CH:19][C:7]([O:8][C:9]2[CH:14]=[CH:13][C:12]([CH:15]([NH2:17])[CH3:16])=[CH:11][CH:10]=2)=[CH:6][CH:5]=1참가 물질
5
실험 절차
1.35 g (4.60 mmol) of 1-[4-(4-difluoromethoxy-phenoxy)-phenyl]-ethanone-oxime were dissolved in 50 ml of 7M methanolic ammonia, then combined with 100 mg Raney nickel. The mixture was shaken overnight at RT and 50 psi hydrogen pressure. The catalyst was removed by suction filtering and the filtrate was evaporated down.
후처리
- customThe catalyst was removed by suction
- filtrationfiltering
- customthe filtrate was evaporated down
출처 및 근거
- ORD 기록
- ord-7e8496d483644c6e97c87d12ee6f25f7
- 출처 데이터셋
- uspto-grants-2014_12
- 특허 번호
- US08916589B2
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