Cysteamine Hydrochloride → 1-Nitro-2-(2-propynylamino)-2-(2-mercaptoethyl)ethylene

반응식

CS[C:3]([NH:8][CH2:9][C:10]#[CH:11])=[CH:4][N+:5]([O-:7])=[O:6].Cl.N[CH2:14][CH2:15][SH:16]>>[N+:5]([CH:4]=[C:3]([NH:8][CH2:9][C:10]#[CH:11])[CH2:14][CH2:15][SH:16])([O-:7])=[O:6]

참가 물질

반응물 2

HCID 9082Cysteamine Hydrochloride

HCID 71401969N-[1-(Methylsulfanyl)-2-nitroethenyl]prop-2-yn-1-amine

생성물 1

HCID 736839981-Nitro-2-(2-propynylamino)-2-(2-mercaptoethyl)ethylene

실험 절차

A solution of the product of Step A of Example 2 is reacted with about an equimolar amount of cysteamine hydrochloride and about two equivalents of base, and the title product is produced.

출처 및 근거

ORD 기록: ord-8782b68346ea4567bdfc9854696deb93
출처 데이터셋: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04250316

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