Potassium Acetate → Cyclopropyldiphenylsulfonium acetate

HRID 1413758노트

반응식

HRID 1413758 반응식
F[B-](F)(F)F.[CH:6]1([S+:9]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:8][CH2:7]1.[C:22]([O-:25])(=[O:24])[CH3:23].[K+]>O>[C:22]([O-:25])(=[O:24])[CH3:23].[CH:6]1([S+:9]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:8][CH2:7]1

참가 물질

4

반응물 2

HCID 517044Potassium AcetateHCID 2724210Cyclopropyldiphenylsulphonium tetrafluoroborate

생성물 1

HCID 20290484Cyclopropyldiphenylsulfonium acetate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a solution of 5.0 g. cyclopropyldiphenylsulfonium tetrafluoroborate in 30 ml. water at 90°-95° C. is added 50 ml. of hot solution of potassium acetate (obtained by mixing 26.6 g. acetic acid with 24.0 g. potassium hydroxide). The reaction mixture is stirred well and maintained at 90°-95° C. for several minutes and allowed to cool to room temperature gradually. The reaction mixture is then filtered free of any solids; the aqueous filtrate extracted several times with methylene chloride, the combined methylene chloride extracts are dried over sodium sulphate, filtered and evaporated i.v. to dryness. From the residue is obtained on trituration with ether the title product, as an oil.

후처리

  1. temperaturemaintained at 90°-95° C. for several minutes
  2. filtrationThe reaction mixture is then filtered free of any solids
  3. extractionthe aqueous filtrate extracted several times with methylene chloride
  4. dry with materialthe combined methylene chloride extracts are dried over sodium sulphate
  5. filtrationfiltered
  6. customevaporated i.v

출처 및 근거

ORD 기록
ord-ac572dcbe8a541288ae0a667cb82eacb
출처 데이터셋
uspto-grants-1981_02
특허 번호
US04251521

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