Ethylenediamine → Imidazo(1,2-a)pyridin-5(1H)-one, 2,3-dihydro-7-phenyl-

HRID 1413813

반응식

C(OCCO)C.Br[C:8]1[N:13]([C:14]2C=CC(C)=C[CH:15]=2)[C:12](=[O:21])[CH:11]=[C:10]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:9]=1.C(N)C[NH2:30]>>[O:21]=[C:12]1[N:13]2[CH2:14][CH2:15][NH:30][C:8]2=[CH:9][C:10]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:11]1

참가 물질

반응물 3

HCID 3301Ethylenediamine

HCID 8076Glycol monoethyl ether

HCID 205708116-Bromo-1-(4-methylphenyl)-4-phenyl-2-pyridone

생성물 1

HCID 3050276Imidazo(1,2-a)pyridin-5(1H)-one, 2,3-dihydro-7-phenyl-

실험 절차

In 3 ml. of 2-ethoxyethanol were refluxed 1.05 g. of 6-bromo-1-(4-methylphenyl)-4-phenyl-2-pyridone and 0.4 g. of ethylenediamine for 5 hours. Then, by treating the reaction mixture as in Example 5, 0.35 g. of 5-oxo-7-phenyl-1,2,3,5-tetrahydroimidazo[1,2-a]pyridine was obtained.

후처리

additionThen, by treating the reaction mixture as in Example 5, 0.35 g

출처 및 근거

ORD 기록: ord-81c2823c709e4f02861c9e2e126c4696
출처 데이터셋: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04251533

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