13beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one → Einecs 227-699-7

HRID 1414971

반응식

HRID 1414971 반응식
[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C:7]1=[CH:6][CH2:5][C:4]2=[O:22])[CH3:2].[H][H]>O1CCOCC1.[Ni]>[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C@@H:7]1[CH2:6][CH2:5][C:4]2=[O:22])[CH3:2]

참가 물질

5

반응물 2

HCID 1097930013beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-oneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 111113Einecs 227-699-7수율 59.6%

시약·촉매·용매 2

HCID 935Nickel촉매HCID 312751,4-Dioxane용매

실험 절차

Dissolve 13β-ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one (2 g) in dioxan (50 cc) containing Raney nickel (ca. 0.5 g) of moderate activity and shake with hydrogen until 160 cc., the amount corresponding to one molecular proportion has been absorbed. Recrystallize the isolated product from methanol to obtain the title product (1.2 g), m.p. 110°-125°; ultraviolet absorption peak at 280 mμ (ε13,200).

후처리

  1. custom, the amount corresponding to one molecular proportion has been absorbed
  2. customRecrystallize the isolated product from methanol

출처 및 근거

ORD 기록
ord-f8615076edb24375a4f9e5b6ba5ce96a
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04002746

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