Ethanolamine → N-(2-hydroxyethyl) tetrabromophthalimide

HRID 1415108

반응식

HRID 1415108 반응식
[Br:1][C:2]1[C:3]([Br:15])=[C:4]([Br:14])[C:5]([Br:13])=[C:6]2[C:11](=[O:12])[O:10][C:8](=O)[C:7]=12.[CH2:16]([CH2:18][NH2:19])[OH:17].O>C1(C)C(C)=CC=CC=1>[OH:17][CH2:16][CH2:18][N:19]1[C:8](=[O:10])[C:7]2=[C:2]([Br:1])[C:3]([Br:15])=[C:4]([Br:14])[C:5]([Br:13])=[C:6]2[C:11]1=[O:12]

참가 물질

5

반응물 3

HCID 700EthanolamineHCID 962Water2회HCID 12443Tetrabromophthalic anhydride

생성물 1

HCID 19812166N-(2-hydroxyethyl) tetrabromophthalimide

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

To a suspension of 464 gm (1 mole) of tetrabromophthalic anhydride in 1.2 liters of xylene was added 61 gm (1 mole) of ethanolamine. The solution was heated and refluxed with a Dean-Stark water separator until the theoretical amount of water separated. The mixture was cooled, diluted with hexane, and filtered. The resulting 413 gm of an off-white solid was washed with hexane and dried at 100° C. This material is used as is for subsequent reactions without further purification.

후처리

  1. temperatureThe solution was heated
  2. customseparated
  3. temperatureThe mixture was cooled
  4. additiondiluted with hexane
  5. filtrationfiltered
  6. washThe resulting 413 gm of an off-white solid was washed with hexane
  7. customdried at 100° C
  8. customas is for subsequent reactions without further purification

출처 및 근거

ORD 기록
ord-28ab706dc0ad4f999b63ddaea580c57f
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04003862

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