Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl chloride → 3-(4-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | Boron trifluoride etherate | HCID 8000 | — |
| 반응물 | N-Hydroxy-4-nitrobenzimidamide | HCID 3825473 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 3-(4-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole | HCID 622484 | — |
반응 단계
A solution of 10.8 g. (0.06 mole) of p-nitrobenzamidoxime and 8.5 g. (0.06 mole) of benzoyl chloride in 250 ml. of dioxane is heated on a steam bath for one hour, followed by the addition of 2 ml. of BF3 -Et2O. After refluxing the solution overnight, the reaction mixture is cooled and the material which precipitates is collected by filtration to yield 8.1 g. (50%) of 5-phenyl-3-(4-nitrophenyl)-1,2,4-oxadizole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04003909 |
| 출처 데이터셋 | uspto-grants-1977_01 |
| ORD ID | ord-901ed1a1bcc743e1b1f1eb34e496da21 |
| 출처 메모 | uspto-grants-1977_01 |