Hydrochloric Acid → HCID 53705343, 화합물

HRID 1415218노트

반응식

HRID 1415218 반응식
[C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])(=[O:3])[CH3:2].[Cl:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[Cl:20])[CH:15]=O.N1CCOCC1.Cl>O.C(O)C>[Cl:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[Cl:20])[CH:15]=[CH:2][C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])=[O:3]

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 8083MorpholineHCID 227103,4-DichlorobenzaldehydeHCID 3364732-Acetyl-1,3-cyclopentanedione

생성물 1

HCID 53705343HCID 53705343, 화합물수율 37.4%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

2-Acetyl-1,3-cyclopentanedione (3.13 g.) was treated with 3,4-dichlorobenzaldehyde (4.36 g.) in 140 ml. of ethanol under reflux for 4 hours in the presence of 5 ml. of morpholine. After cooling, the reaction mixture was poured into 150 ml. of water containing 7 ml. of conc. hydrochloric acid. Deposited crystals were separated by filtration and washed with water, and dried. 2-(3,4-Dichlorocinnamoyl)-1,3-cyclopentanedione (2.48 g., 37%) was obtained which showed mp. 190°- 191° C. after recrystallization from dioxane.

후처리

  1. temperatureAfter cooling
  2. additionthe reaction mixture was poured into 150 ml
  3. customDeposited crystals were separated by filtration
  4. washwashed with water
  5. customdried

출처 및 근거

ORD 기록
ord-0cc9c682c8d6438daabb77fa6f991bab
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04003936

반응 노트

불러오는 중…