1-Methylpiperazine → 8-bromo-1-{3-methyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-1H-pyrazol-4-yl}-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

반응식

[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[nH:12][c:13](=[O:25])[n:14]3-[c:15]1[c:16]([CH3:24])[n:17][n:18]([CH2:20][C:21](=[O:22])[OH:23])[cH:19]1.[CH3:26][N:27]1[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[nH:12][c:13](=[O:25])[n:14]3-[c:15]1[c:16]([CH3:24])[n:17][n:18]([CH2:20][C:21](=[O:23])[N:30]2[CH2:29][CH2:28][N:27]([CH3:26])[CH2:32][CH2:31]2)[cH:19]1

참가 물질

반응물 2

HCID 531671-Methylpiperazine

HCID 59619756[4-(8-Bromo-2-oxo-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-3-methyl-pyrazol-1-yl]-acetic acid

생성물 1

HCID 596198958-bromo-1-{3-methyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-1H-pyrazol-4-yl}-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

출처 및 근거

ORD 기록: ord-a54dc515bbfd404a919e1eaa1ef2c62e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…