Trimethylsilyl cyanide → alpha-(3-Fluoro-4-methoxyphenyl)-alpha-(4-sulfamoylanilino)acetonitrile
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[F:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH:5]=[N:6][C:7]1[CH:12]=[CH:11][C:10]([S:13](=[O:16])(=[O:15])[NH2:14])=[CH:9][CH:8]=1.C[Si]([C:26]#[N:27])(C)C>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]([NH:6][C:7]2[CH:8]=[CH:9][C:10]([S:13](=[O:16])(=[O:15])[NH2:14])=[CH:11][CH:12]=2)[C:26]#[N:27])[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]참가 물질
3
실험 절차
Following a procedure similar to that described in Example 1(ii), but using N-(3-fluoro-4-methoxybenzylidene)-4-sulfamoylaniline [prepared as described in step (i) above] and trimethylsilyl cyanide as starting materials, the title compound was obtained as a slightly yellow powder (yield 98%).
출처 및 근거
- ORD 기록
- ord-b73fd7d6abd54b79a0266bc5f55a25dc
- 출처 데이터셋
- uspto-grants-1999_06
- 특허 번호
- US05908858
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