Hydrogen Bromide → 6-Hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid
반응식
C([O:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[CH:18]=[C:17]([C:22]([OH:24])=[O:23])[CH:16]=[CH:15]2)CCCCCCCCC.Br>C(O)(=O)C>[OH:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[CH2:18][CH:17]([C:22]([OH:24])=[O:23])[CH2:16][CH2:15]2참가 물질
4
실험 절차
16.6 g (50 mmol) of the 6-decyloxynaphthalene-2-carboxylic acid obtained in the first stage was heated under reflux at 130° C. for 7 hours in the presence of 250 cc of acetic acid and 86.5 g (0.5 mol) of 47% hydrobromic acid. To the reaction mixture was added distilled water, and then the resulting mixture was concentrated under reduced pressure to obtain 10.60 g (50 mmol) of 1,2,3,4-tetrahydro-6-hydroxynaphthalene-2-carboxylic acid.
후처리
- temperaturewas heated
- additionTo the reaction mixture was added
- distillationdistilled water
- concentrationthe resulting mixture was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-528cd02b7f3644e7b8e580a1f266c8a1
- 출처 데이터셋
- uspto-grants-1998_03
- 특허 번호
- US05725798
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