Pyridine → 1,3,5-Triiodobenzene-2,4,6-trialdehyde
반응식
[I:1][C:2]1[C:7]([CH2:8][OH:9])=[C:6]([I:10])[C:5]([CH2:11][OH:12])=[C:4]([I:13])[C:3]=1[CH2:14][OH:15].C(N(CC)CC)C.N1C=CC=CC=1>CS(C)=O>[I:1][C:2]1[C:3]([CH:14]=[O:15])=[C:4]([I:13])[C:5]([CH:11]=[O:12])=[C:6]([I:10])[C:7]=1[CH:8]=[O:9]참가 물질
5
반응 조건
- 온도
- 0 °C
실험 절차
1,3,5-Triiodo-2,4,6-trihydroxymethylbenzene (4.5 g, 8.2 mmol) was dissolved in DMSO (80 ml). Triethylamine (51.7 ml, 371 mmol) and pyridine.SO3 (11.8 g, 74.2 mmol) were added and the mixture was stirred for two hours. The two phases were separated and the lower phase was cooled to 0° C., poured into water (150 ml) and stirred for 30 min at 0° C. The white solid was collected by filtration, washed with water and dried. Yield: 3.0 g (67%).
후처리
- additionSO3 (11.8 g, 74.2 mmol) were added
- customThe two phases were separated
- additionpoured into water (150 ml)
- stirringstirred for 30 min at 0° C
- filtrationThe white solid was collected by filtration
- washwashed with water
- customdried
출처 및 근거
- ORD 기록
- ord-bfed357575d64ceebe141e406e37ff24
- 출처 데이터셋
- uspto-grants-1999_03
- 특허 번호
- US05882628
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