Benzyl Bromide → HCID 69471538, 화합물

HRID 1420132노트

반응식

HRID 1420132 반응식
[F:1][CH2:2][C:3]([NH2:5])=[S:4].[CH2:6]([Br:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>C(Cl)(Cl)Cl.CCOCC>[BrH:13].[CH2:6]([S:4][C:3](=[NH:5])[CH2:2][F:1])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

참가 물질

5

반응물 2

HCID 7498Benzyl BromideHCID 167372062-Fluorothioacetamide

생성물 1

HCID 69471538HCID 69471538, 화합물수율 54%

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 6212Chloroform용매

실험 절차

Fluorothioacetamide (3.39 g) and benzyl bromide (6.23 g) were refluxed in chloroform (40 ml), under nitrogen, for 16 h. After cooling, the mixture was diluted with ether (200 ml) and the resulting orange solid filtered off. The solid was washed with more ether and dried over P2O5 in vacuo to give 5.19 g of the desired product.

후처리

  1. temperatureAfter cooling
  2. filtrationthe resulting orange solid filtered off
  3. washThe solid was washed with more ether
  4. dry with materialdried over P2O5 in vacuo

출처 및 근거

ORD 기록
ord-93a754e113f9425abbc9ad40dd8b8ff7
출처 데이터셋
uspto-grants-1999_03
특허 번호
US05889056

반응 노트

불러오는 중…