Hydrochloric Acid → Allyl 4-bromobutyrate
반응식
[Br:1][CH2:2][CH2:3][CH2:4][C:5](Cl)=[O:6].C([OH:11])C=C.N1C=C[CH:15]=[CH:14][CH:13]=1.Cl>ClCCl>[Br:1][CH2:2][CH2:3][CH2:4][C:5]([O:6][CH2:13][CH:14]=[CH2:15])=[O:11]참가 물질
6
실험 절차
4-Bromobutryl chloride (18.6 g) was treated with allyl alcohol (5.8 g) in the presence of pyridine (8 g) in dry dichloromethane at 0° C. for 0.5 hours. The solution was treated with aqueous HCl and warmed to room temperature. The organic layer was separated, washed with saturated aqueous brine, dried (MgSO4) and evaporated to give the title compound as a colourless oil, 19.7 g, 95% yield
후처리
- customThe organic layer was separated
- washwashed with saturated aqueous brine
- dry with materialdried (MgSO4)
- customevaporated
출처 및 근거
- ORD 기록
- ord-9190722aae10416280c7065235af5f40
- 출처 데이터셋
- uspto-grants-2000_06
- 특허 번호
- US06071899
반응 노트
불러오는 중…