Bromine → HCID 9906877, 화합물

HRID 1420770노트

반응식

HRID 1420770 반응식
[Br:1]Br.[CH3:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[C:21]3[N:20]4[C:16](=[CH:17][CH:18]=[CH:19]4)[C:15](=[O:22])[C:14]=3[S:13][CH:12]=2)=[CH:7][CH:6]=1>C(Cl)(Cl)Cl>[Br:1][C:18]1[CH:17]=[C:16]2[N:20]([C:21]3[C:11]([C:8]4[CH:7]=[CH:6][C:5]([O:4][CH3:3])=[CH:10][CH:9]=4)=[CH:12][S:13][C:14]=3[C:15]2=[O:22])[CH:19]=1

참가 물질

4

반응물 2

HCID 24408BromineHCID 3854553-(4-Methoxyphenyl)-8H-thieno[2,3-b]pyrrolizin-8-one

생성물 1

HCID 9906877HCID 9906877, 화합물

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

2.1 mmol of bromine are added to a solution of 1.8 mmol of 3-(4-methoxyphenyl)-8H-thieno[2.3-b]pyrrolizin-8-one in 50 ml of chloroform. After two hours' stirring the solvent is evaporated off under reduced pressure. Chromatography on silica gel (dichloromethane) allows the expected product to be isolated.

후처리

  1. customis evaporated off under reduced pressure
  2. customto be isolated

출처 및 근거

ORD 기록
ord-bc7d2541b3bb40c9b6339911f59b64cd
출처 데이터셋
uspto-grants-2000_06
특허 번호
US06071945

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