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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Furan-2-carboxylic acid (7-bromo-2,3-dimethoxy-quinoxalin-5-ylmethyl)-amide → Furan-2-carboxylic acid (7-bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amide

HRID 1422229
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인쇄 미리보기

반응식

HRID 1422229 반응식
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([N:6]=[C:7]([O:14]C)[C:8]([O:12]C)=[N:9]2)=[C:4]([CH2:16][NH:17][C:18]([C:20]2[O:21][CH:22]=[CH:23][CH:24]=2)=[O:19])[CH:3]=1>Br.C(O)(=O)C.C(OCC)C>[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([NH:6][C:7](=[O:14])[C:8](=[O:12])[NH:9]2)=[C:4]([CH2:16][NH:17][C:18]([C:20]2[O:21][CH:22]=[CH:23][CH:24]=2)=[O:19])[CH:3]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 1

HCID 54513571Furan-2-carboxylic acid (7-bromo-2,3-dimethoxy-quinoxalin-5-ylmethyl)-amide

생성물 1

HCID 44363734Furan-2-carboxylic acid (7-bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amide

시약·촉매·용매 3

HCID 176Acetic Acid용매HCID 260Hydrogen Bromide용매HCID 3283Diethyl Ether용매

실험 절차

310 mg (0.79 mmol) of furan-2-carboxylic acid (7-bromo-2,3-dimethoxy-quinoxalin-5-ylmethyl)-amide are dissolved in 6 ml of an approximately 25% solution of hydrogen bromide in acetic acid, and the solution is stirred at room temperature for 16 hours. The mixture is diluted with diethyl ether, and the solid is filtered off and washed with diethyl ether. After drying under a high vacuum, the title compound is obtained in the form of a beige solid.

후처리

  1. filtrationthe solid is filtered off
  2. washwashed with diethyl ether
  3. customAfter drying under a high vacuum

출처 및 근거

ORD 기록
ord-c842bfe9f6f949ed8e0ffc238432dd90
출처 데이터셋
uspto-grants-2000_06
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US06080743

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