1,2,3,6,-tetrahydro-N-(2-hydroxyethyl)phthalimide → HCID 10896667, 화합물

HRID 1422265노트

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HRID 1422265 반응식
[OH:1][CH2:2][CH2:3][N:4]1[C:8](=[O:9])[CH:7]2[CH2:10][CH:11]=[CH:12][CH2:13][CH:6]2[C:5]1=[O:14].[C:15]([O:30]CC(C)C)(=O)[CH:16]1[CH2:28][CH:27]=[CH:26][CH2:25][CH:17]1[C:18]([O:20][CH2:21][CH:22](C)C)=[O:19]>[O-]CCCC.[O-]CCCC.[O-]CCCC.[O-]CCCC.[Ti+4].O>[C:18]([O:20][CH2:21][CH2:22][N:4]1[C:5](=[O:14])[CH:6]2[CH2:13][CH:12]=[CH:11][CH2:10][CH:7]2[C:8]1=[O:9])(=[O:19])[CH:17]1[CH2:25][CH:26]=[CH:27][CH2:28][CH:16]1[C:15]([O:1][CH2:2][CH2:3][N:4]1[C:8](=[O:9])[CH:7]2[CH2:10][CH:11]=[CH:12][CH2:13][CH:6]2[C:5]1=[O:14])=[O:30]

참가 물질

5

반응물 2

HCID 858511,2,3,6,-tetrahydro-N-(2-hydroxyethyl)phthalimideHCID 6432739Diisobutyl 1,2,3,6-tetrahydrophthalate

생성물 1

HCID 10896667HCID 10896667, 화합물수율 101%

시약·촉매·용매 2

HCID 21801Titanium tetrabutoxide촉매HCID 962Water용매

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온도
230 °C

실험 절차

N-(2-Hydroxyethyl)-1,2,3,6-tetrahydrophthalimide (195.2 g, 1 mol) was dissolved in diisobutyl 1,2,3,6-tetrahydrophthalate (141.2 g, 0.5 mol). The mixture was kept at 150° C. under vacuum to eliminate any traces of water. Titanium tetrabutoxide (1.7 g) was added under atmospheric pressure and the transesterification reaction was carried out distilling off the isobutyl alcohol formed. As the reaction proceeded the temperature was increased stepwise to 230° C. and the pressure was lowered to 20 Torr (26.7 mbar). After ca. 24 h, 265 g of brown crude bis[2-(1,2,3,6-tetrahydrophthalimido)ethyl] 1,2,3,6-tetrahydrophthalate were obtained.

후처리

  1. customwas kept at 150° C. under vacuum
  2. customthe transesterification reaction
  3. distillationwas carried out distilling off the isobutyl alcohol
  4. customformed

출처 및 근거

ORD 기록
ord-2ed3f2956efc461882cb3ca99b5c14d4
출처 데이터셋
uspto-grants-2000_06
특허 번호
US06080872

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