Dimethylformamide dimethyl acetal → HCID 86705039, 화합물

HRID 1427210노트

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HRID 1427210 반응식
[F:1][C:2]1[CH:3]=[C:4]([N+:12]([O-:14])=[O:13])[C:5]([CH3:11])=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1.CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>CN(C)C=O>[F:1][C:2]1[CH:3]=[C:4]([N+:12]([O-:14])=[O:13])[C:5]([CH:11]=[CH:17][N:18]([CH3:20])[CH3:19])=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1

참가 물질

4

반응물 2

HCID 78373Dimethylformamide dimethyl acetalHCID 184653725-Fluoro-2-methyl-1,3-dinitrobenzene

생성물 1

HCID 86705039HCID 86705039, 화합물수율 94%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

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온도
120 °C

실험 절차

To a solution of 5-fluoro-2-methyl-1,3-dinitrobenzene (15 g, 0.075 mol) in N,N-dimethylformamide (300 mL) was added dimethylformamide dimethylacetal (89 g, 0.75 mol). The bright red reaction mixture was heated at 120° C. for 5 h, then concentrated in vacuo to provide 18 g crude product, which was used in the next step without further purification. LC/MS m/z=256.2 [M+H]+.

후처리

  1. customThe bright red reaction mixture
  2. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-62b6a284456b44b584058394e44eb75c
출처 데이터셋
uspto-grants-2015_01
특허 번호
US08933113B2

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