Diisopropylethylamine → N-[4-(2-Amino-5-{4-[(2R)-1,4-dioxan-2-ylmethoxy]-3-methoxyphenyl}pyridin-3-yl)phenyl]-1-(2-fluoroethyl)-4-oxo-5-phenyl-1,4-dihydropyridine-3-carboxamide

반응식

CCN(C(C)C)C(C)C.[F:10][CH2:11][CH2:12][N:13]1[CH:18]=[C:17]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:16](=[O:25])[C:15]([C:26]([OH:28])=O)=[CH:14]1.CCOC(C(C#N)=NOC(N1CCOCC1)=[N+](C)C)=O.F[P-](F)(F)(F)(F)F.[NH2:56][C:57]1[CH:62]=[CH:61][C:60]([C:63]2[C:64]([NH2:85])=[N:65][CH:66]=[C:67]([C:69]3[CH:74]=[CH:73][C:72]([O:75][CH2:76][C@H:77]4[CH2:82][O:81][CH2:80][CH2:79][O:78]4)=[C:71]([O:83][CH3:84])[CH:70]=3)[CH:68]=2)=[CH:59][CH:58]=1>CN(C=O)C.O>[NH2:85][C:64]1[C:63]([C:60]2[CH:59]=[CH:58][C:57]([NH:56][C:26]([C:15]3[C:16](=[O:25])[C:17]([C:19]4[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=4)=[CH:18][N:13]([CH2:12][CH2:11][F:10])[CH:14]=3)=[O:28])=[CH:62][CH:61]=2)=[CH:68][C:67]([C:69]2[CH:74]=[CH:73][C:72]([O:75][CH2:76][C@H:77]3[CH2:82][O:81][CH2:80][CH2:79][O:78]3)=[C:71]([O:83][CH3:84])[CH:70]=2)=[CH:66][N:65]=1