Phenol → 2-sec-Butylphenol

HRID 1429105

반응식

HRID 1429105 반응식
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:8][C:9](=[CH2:11])[CH3:10].[CH2:12]=[CH:13][CH2:14][CH3:15].CC(C)C>[O-2].[Al+3].[O-2].[O-2].[Al+3]>[CH:13]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[OH:7])([CH2:14][CH3:15])[CH3:12].[CH:13]([C:2]1[CH:3]=[C:4]([C:9]([CH3:10])([CH3:8])[CH3:11])[CH:5]=[CH:6][C:1]=1[OH:7])([CH2:14][CH3:15])[CH3:12]

참가 물질

7

반응물 4

HCID 996Phenol2회HCID 6360IsobutaneHCID 78441-Butene2회HCID 8255Isobutylene2회

생성물 2

HCID 69842-sec-ButylphenolHCID 5262072-(1-Methylpropyl)-4-tert-butylphenol

시약·촉매·용매 1

HCID 9989226Alumina촉매

반응 조건

온도
220 °C

실험 절차

105 g of phenol and 5.0 g of aluminum oxide catalyst that was calcined in air at a temperature of 450° C. was charged in an autoclave and heated to 220° C. A raffinate stream containing 82.4% isobutylene, 1.3% 1-butene, and 16.3% isobutane was then charged over a period of 3 hours. The amount of raffinate charged was 70 g with an isobutylene to phenol mole ratio of 1.13:1. The yield of OTBP at the end of 6 hours was 50.41%, down from 52% at the 5-hour mark. The amount of 1-butene in the feed that reacted to form 2-sec-butylphenol and 2-sec-butyl-4-tert-butylphenol was 44.5%. The amount of the two sec-butylphenol impurities (2-sec-butylphenol and 2-sec-butyl-4-tert-butylphenol) were 0.44 area percent and 0.15%, respectively.

후처리

  1. customwas calcined in air at a temperature of 450° C.
  2. additionwas charged in an autoclave
  3. additionwas then charged over a period of 3 hours
  4. additionThe amount of raffinate charged
  5. customat the end of 6 hours
  6. customat the 5-hour mark

출처 및 근거

ORD 기록
ord-93a7ea69d90e4b77bb10a0189c93b5ef
출처 데이터셋
uspto-grants-2015_01
특허 번호
US08937201B2

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