Formaldehyde → 6-tert-butyl-8-fluoro-2-(2-hydroxymethyl-3-{1-methyl-5-[5-(6-methyl-2,6-diaza-spiro[3.3]hept-2-yl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-pyridazin-3-yl}-phenyl)-2H-phthalazin-1-one

반응식

[CH2:1]1[C:4]2([CH2:7][NH:6][CH2:5]2)[CH2:3][N:2]1[C:8]1[CH:9]=[CH:10][C:11]([NH:14][C:15]2[C:20](=[O:21])[N:19]([CH3:22])[N:18]=[C:17]([C:23]3[C:24]([CH2:45][OH:46])=[C:25]([N:29]4[N:38]=[CH:37][C:36]5[C:31](=[C:32]([F:43])[CH:33]=[C:34]([C:39]([CH3:42])([CH3:41])[CH3:40])[CH:35]=5)[C:30]4=[O:44])[CH:26]=[CH:27][CH:28]=3)[CH:16]=2)=[N:12][CH:13]=1.C=O.[C:49]([BH3-])#N.[Na+]>CO>[C:39]([C:34]1[CH:35]=[C:36]2[C:31](=[C:32]([F:43])[CH:33]=1)[C:30](=[O:44])[N:29]([C:25]1[CH:26]=[CH:27][CH:28]=[C:23]([C:17]3[CH:16]=[C:15]([NH:14][C:11]4[CH:10]=[CH:9][C:8]([N:2]5[CH2:3][C:4]6([CH2:7][N:6]([CH3:49])[CH2:5]6)[CH2:1]5)=[CH:13][N:12]=4)[C:20](=[O:21])[N:19]([CH3:22])[N:18]=3)[C:24]=1[CH2:45][OH:46])[N:38]=[CH:37]2)([CH3:40])([CH3:41])[CH3:42]