Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Acetyltryptamine → N-(2-{2-[(3,5-Difluoro-phenyl)-(4-hydroxy-5-isopropyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-methyl]-1H-indol-3-yl}-ethyl)-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Acetyltryptamine | HCID 70547 | — |
| 반응물 | 3,5-Difluorobenzaldehyde | HCID 588160 | — |
| 반응물 | 4-Hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one | HCID 56604111 | — |
| 생성물 | N-(2-{2-[(3,5-Difluoro-phenyl)-(4-hydroxy-5-isopropyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-methyl]-1H-indol-3-yl}-ethyl)-acetamide | HCID 57933437 | — |
반응 단계
Using general procedure C, 4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one (Lit. 11) was reacted with 3,5-difluoro-benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as a yellow solid. MS: 468.0 ([M+H]+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07612099B2 |
| 출처 데이터셋 | uspto-grants-2009_11 |
| ORD ID | ord-fa2debcb10114808bd803f826d398071 |
| 출처 메모 | uspto-grants-2009_11 |