Hydrochloric Acid → 2-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride

HRID 1432534노트

반응식

HRID 1432534 반응식
[CH:1]([C:4]1[S:8][C:7]([NH:9][S:10]([C:13]2[CH:14]=[C:15]3[C:19](=[CH:20][CH:21]=2)[CH2:18][CH:17]([NH:22]C(=O)C)[CH2:16]3)(=[O:12])=[O:11])=[N:6][N:5]=1)([CH3:3])[CH3:2].[ClH:26]>>[ClH:26].[CH:1]([C:4]1[S:8][C:7]([NH:9][S:10]([C:13]2[CH:14]=[C:15]3[C:19](=[CH:20][CH:21]=2)[CH2:18][CH:17]([NH2:22])[CH2:16]3)(=[O:12])=[O:11])=[N:6][N:5]=1)([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 57933501N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide

생성물 1

HCID 672312832-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride

실험 절차

N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide (96 mg) was heated and stirred for 27 hours in 10 ml 2N hydrochloric acid at 100° C. After completion a clear solution occurred. This was evaporated to dryness and the solid residue was used without further purification.

후처리

  1. customThis was evaporated to dryness
  2. customthe solid residue was used without further purification

출처 및 근거

ORD 기록
ord-195da3575622433db7aba25ba3d389bf
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07612104B2

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