Sodium borohydride → HCID 57936239, 화합물

HRID 1435016노트

반응식

HRID 1435016 반응식
[CH3:1][C:2]1([CH3:27])[CH2:7][CH:6]([NH:8][C:9]2[N:14]=[C:13]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][C:22](=[O:24])[CH3:23])=[CH:17][CH:16]=3)[CH:12]=[CH:11][N:10]=2)[CH2:5][C:4]([CH3:26])([CH3:25])[NH:3]1.[BH4-].[Na+]>CO>[CH3:26][C:4]1([CH3:25])[CH2:5][CH:6]([NH:8][C:9]2[N:14]=[C:13]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH:22]([OH:24])[CH3:23])=[CH:17][CH:16]=3)[CH:12]=[CH:11][N:10]=2)[CH2:7][C:2]([CH3:27])([CH3:1])[NH:3]1

참가 물질

4

반응물 2

HCID 4311764Sodium borohydrideHCID 57936231HCID 57936231, 화합물

생성물 1

HCID 57936239HCID 57936239, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

The title compound was prepared by reduction of {4-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-phenyl}-propan-2-one with sodium borohydride in MeOH. Yield: 32 mg (100%).

출처 및 근거

ORD 기록
ord-590d389527aa42f5bc9ba155a1f4015d
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07615562B2

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