Acetic Anhydride → HCID 53964927, 화합물

HRID 1438931노트

반응식

HRID 1438931 반응식
[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][C:10]([C:15](=[O:22])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:11]([OH:14])[CH:12]=2)[CH2:7][CH2:6]1)=[O:4].[C:23](OC(=O)C)(=[O:25])[CH3:24]>>[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][C:10]([C:15](=[O:22])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:11]([O:14][C:23](=[O:25])[CH3:24])[CH:12]=2)[CH2:7][CH2:6]1)=[O:4]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 54109752HCID 54109752, 화합물

생성물 1

HCID 53964927HCID 53964927, 화합물

실험 절차

A solution of 10 g of 5-benzoyl-6-hydroxy-indane-1-carboxylic acid methyl ester in 100 ml of acetic anhydride is heated to the reflux temperature for 4 hours under anhydrous conditions. It is then evaporated to dryness in vacuo. The evaporation residue is mixed with 200 ml of toluene and evaporated in vacuo. Distillation of the evaporation residue in a high vacuum gives, in the fraction boiling at 195°-200° C/0.06 /mm Hg, 5-benzoyl-6-acetoxy-indane-1-carboxylic acid methyl ester in the form of a colourless oil.

후처리

  1. customIt is then evaporated to dryness in vacuo
  2. additionThe evaporation residue is mixed with 200 ml of toluene
  3. customevaporated in vacuo
  4. distillationDistillation of the evaporation residue in a high vacuum

출처 및 근거

ORD 기록
ord-387e321adbf940e7b75503054513a784
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04057573

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