Ethylenediamine → [1,5-Di-(4-isopropylcyclohexyl)-3-pentyl]-1,4,8-triazaoctane

HRID 1439773노트

반응식

HRID 1439773 반응식
[NH2:1][CH2:2][CH2:3][NH2:4].[CH:5]([CH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16](=O)[CH2:17][CH2:18][CH:19]2[CH2:24][CH2:23][CH:22]([CH:25]([CH3:27])[CH3:26])[CH2:21][CH2:20]2)[CH2:10][CH2:9]1)([CH3:7])[CH3:6].[C:29](#[N:32])[CH:30]=[CH2:31]>>[CH:5]([CH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][CH:16]([NH:1][CH2:2][CH2:3][NH:4][CH2:31][CH2:30][CH2:29][NH2:32])[CH2:17][CH2:18][CH:19]2[CH2:24][CH2:23][CH:22]([CH:25]([CH3:27])[CH3:26])[CH2:21][CH2:20]2)[CH2:10][CH2:9]1)([CH3:7])[CH3:6]

참가 물질

4

반응물 3

HCID 3301EthylenediamineHCID 7855AcrylonitrileHCID 213966471,5-Bis[4-(propan-2-yl)cyclohexyl]pentan-3-one

생성물 1

HCID 21396682[1,5-Di-(4-isopropylcyclohexyl)-3-pentyl]-1,4,8-triazaoctane

실험 절차

As an alternative to obtaining a mixture of Schiff bases VI and VI(a) or VI(b), the reaction can be conducted stepwise. For example, 1,2-diaminoethane may be converted to a Schiff base with 1,5-di-(4-isopropylcyclohexyl)-3-pentanone, catalytically reduced, then the ring nitrogen selectively cyanoethylated with acrylonitrile, followed by catalytic hydrogenation to furnish [1,5-di-(4-isopropylcyclohexyl)-3-pentyl]-1,4,8-triazaoctane.

후처리

  1. customAs an alternative to obtaining
  2. customthe reaction

출처 및 근거

ORD 기록
ord-3a0d87aa058449b180688ab48e252a21
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04060639

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