Butyl bromide → 1-p-Chlorophenyl-1-n-butoxy-2-(1,2,4-triazol-1-yl)ethane

HRID 1447023노트

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([OH:15])[CH2:9][N:10]2[CH:14]=[N:13][CH:12]=[N:11]2)=[CH:4][CH:3]=1.[H-].[Na+].[CH2:18](Br)[CH2:19][CH2:20][CH3:21]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([O:15][CH2:18][CH2:19][CH2:20][CH3:21])[CH2:9][N:10]2[CH:14]=[N:13][CH:12]=[N:11]2)=[CH:4][CH:3]=1

참가 물질

반응물 3

HCID 8002Butyl bromide

HCID 24758Sodium hydride

HCID 5580621-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol

생성물 1

HCID 136554241-p-Chlorophenyl-1-n-butoxy-2-(1,2,4-triazol-1-yl)ethane

실험 절차

Following the procedure of Example 9, Step 2, 1-p-chlorophenyl-2-(1,2,4-triazol-1-yl)-ethanol (2.23 g), sodium hydride (440 mg; 50%) and n-butyl bromide (1.37 g) were reacted to give the title compound as an oil.

후처리

customwere reacted

출처 및 근거

ORD 기록: ord-29f5a430a5e542b3ae0a042773fc0f57
출처 데이터셋: uspto-grants-1982_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04315016

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