Hydrochloric Acid → HCID 53684414, 화합물

HRID 1447200노트

반응식

HRID 1447200 반응식
CCN(C1C=CC=CC=1)CC.Cl[C:13]([O:15][CH3:16])=[O:14].[CH3:17][C:18]([CH3:25])=[CH:19][CH:20]=[N:21][CH:22]([CH3:24])[CH3:23].Cl>C1(C)C=CC=CC=1.O>[CH3:16][O:15][C:13](=[O:14])[N:21]([CH:22]([CH3:24])[CH3:23])[CH:20]=[CH:19][C:18]([CH3:25])=[CH2:17]

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 6586Methyl chloroformateHCID 7061N,N-DiethylanilineHCID 13061751HCID 13061751, 화합물

생성물 1

HCID 53684414HCID 53684414, 화합물

시약·촉매·용매 2

HCID 962Water용매HCID 1140Toluene용매2회

실험 절차

To a stirred solution of 657 g diethylaniline in 2 liter toluene is added dropwise over ca. 5 minutes 416 g methyl chloroformate. Then to the stirred mixture 500 g N-(3-methyl-2-butenyliden)-isopropylamine in 500 ml toluene is added dropwise over 2 hours, maintaining the temperature between 25° and 30° C. Stirring is continued for 1 hour upon completion of the addition and the reaction mixture is treated with 400 ml of water and 90 ml conc. hydrochloric acid. The organic phase is washed with 600 ml of saturated aqueous sodium bicarbonate solution and with 600 ml water, dried and evaporated in vacuo to give the heading compound.

후처리

  1. temperaturemaintaining the temperature between 25° and 30° C
  2. additionis continued for 1 hour upon completion of the addition
  3. washThe organic phase is washed with 600 ml of saturated aqueous sodium bicarbonate solution and with 600 ml water
  4. customdried
  5. customevaporated in vacuo
  6. customto give the heading compound

출처 및 근거

ORD 기록
ord-efc4a1e9a62b42598dca9797fa9dc3c5
출처 데이터셋
uspto-grants-1982_02
특허 번호
US04316042

반응 노트

불러오는 중…