Toluene → 6-Chloro-2,4-dinitrophenyl urea

HRID 1447323

반응식

HRID 1447323 반응식
[Cl:1][C:2]1[C:7]([NH2:8])=[C:6]([N+:9]([O-:11])=[O:10])[CH:5]=[C:4]([N+:12]([O-:14])=[O:13])[CH:3]=1.C1(C)C=CC=CC=1.ClS([N:26]=[C:27]=[O:28])(=O)=O>O>[Cl:1][C:2]1[C:7]([NH:8][C:27]([NH2:26])=[O:28])=[C:6]([N+:9]([O-:11])=[O:10])[CH:5]=[C:4]([N+:12]([O-:14])=[O:13])[CH:3]=1

참가 물질

5

반응물 3

HCID 1140TolueneHCID 190526-Chloro-2,4-dinitroanilineHCID 70918Chlorosulfonyl isocyanate

생성물 1

HCID 202599016-Chloro-2,4-dinitrophenyl urea

시약·촉매·용매 1

HCID 962Water용매

실험 절차

370 Parts of 6-chloro-2,4-dinitroaniline are stirred for 4 hours at 80° C. in 2600 parts of toluene with 312 parts of chlorosulfonyl isocyanate. At 25° C., 360 parts of water are added to the resulting suspension of N-6-chloro-2,4-dinitrophenyl-N'-chlorosulfonyl urea without intermediate isolation, and the mixture is saponified at 60° C. within 4 hours to yield 6-chloro-2,4-dinitrophenyl urea. After diluting said mixture with water, it is neutralized with 33% sodium hydroxide solution, filtered while hot, and the product is thoroughly washed with hot toluene and water. After drying in vacuo, there are obtained 383 parts of 6-chloro-2,4-dinitrophenyl urea having a melting point of from 219° to 221° C.

출처 및 근거

ORD 기록
ord-754d301b59f54f50953c5879751c27cd
출처 데이터셋
uspto-grants-1982_02
특허 번호
US04316861

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